Evaluation of telavancin dose capping in a large community hospital
نویسندگان
چکیده
800. Improving Definitive Therapy Among Patients with Methicillin-resistant Staphylococcus aureus Bloodstream Infections: Predictors of Early Therapeutic Switch to Linezolid or Daptomycin Marin Schweizer, PhD; Kelly Richardson, PhD; Mary Vaughan Sarrazin, PhD; Michael Jones, PhD; Daniel Livorsi, MD, MSc; Rajeshwari Nair, MBBS, PhD; Michihiko Goto, MD, MSCI; Bruce Alexander, PharmD; Brice Beck, MA and Eli Perencevich, MD, MS, FIDSA, FSHEA; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, Iowa City VA Health Care System, Iowa City, Iowa, Iowa City VA Medical Center, Iowa City, Iowa, University of Iowa, Iowa City, Iowa, Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa
منابع مشابه
Clinical utility of telavancin for treatment of hospital-acquired pneumonia: focus on non-ventilator-associated pneumonia
BACKGROUND Hospital-acquired pneumonia (HAP) is the most common health care-associated infection contributing to death. Studies have indicated that there may be differences in the causative pathogens and outcomes of ventilator-associated pneumonia (VAP) and non-ventilator-associated pneumonia (NV-HAP). However, with limited NV-HAP-specific data available, treatment is generally based on data fr...
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Background: Dose calculation algorithms play a very important role in predicting the explicit dose distribution. We evaluated the percent depth dose (PDD), lateral depth dose profile, and surface dose volume histogram in inhomogeneous media using calculation algorithms and inhomogeneity correction methods. Materials and Methods: The homogeneous and inhomogeneous virtual slab phantoms used in th...
متن کاملPotential Role for Telavancin in Bacteremic Infections Due to Gram-Positive Pathogens: Focus on Staphylococcus aureus
Staphylococcus aureus bacteremia (SAB) is one of the most common serious bacterial infections and the most frequent invasive infection due to methicillin-resistant S. aureus (MRSA). Treatment is challenging, particularly for MRSA, because of limited treatment options. Telavancin is a bactericidal lipoglycopeptide antibiotic that is active against a range of clinically relevant gram-positive pat...
متن کاملCost-effectiveness of telavancin versus vancomycin for treatment of complicated skin and skin structure infections.
STUDY OBJECTIVE To determine the cost-effectiveness of telavancin versus vancomycin for the treatment of complicated skin and skin structure infections (cSSSIs). DESIGN Pharmacoeconomic analysis conducted from the hospital's perspective using data from the Assessment of Telavancin in Complicated Skin and Skin Structure Infections (ATLAS) phase III clinical trial. SETTING One hundred twenty-...
متن کاملMultiple-dose pharmacokinetics of intravenous telavancin in healthy male and female subjects.
OBJECTIVES The aim of this study was to assess the steady-state pharmacokinetic parameters of telavancin, an investigational bactericidal lipoglycopeptide, after intravenous (iv) administration to healthy male and female subjects. PATIENTS AND METHODS In a randomized, double-blind, parallel-group, gender-stratified, two-dose study, 79 adult subjects received three daily 60 min iv infusions of...
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عنوان ژورنال:
دوره 4 شماره
صفحات -
تاریخ انتشار 2017